BDBM562390 (+)-4-chloro-3-ethyl-7-{3-[(6-fluoronaphthalen-1-yl)oxy]propyl}-2,14-dimethyl-15-[2-(oxan-4-yl)ethyl]-13,13-dioxo-10,11,12,13,14,15-hexahydro-2H-13lambda6-pyrazolo[3',4':4,5][1,2,8]thiadiazacycloundecino[6,7,8-hi]indole-8-carboxylic acid (Enantiomer 1)::US11401278, Example 61
SMILES CCc1c-2c(nn1C)C(CCC1CCOCC1)N(C)S(=O)(=O)CCCn1c(C(O)=O)c(CCCOc3cccc4cc(F)ccc34)c3ccc(Cl)c-2c13
InChI Key InChIKey=LAWVJPDUZILMPR-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 562390
TargetBcl-2-like protein 1/Bcl2-associated agonist of cell death [103-127,M117N](Homo sapiens (Human))
The Broad Institute
US Patent
The Broad Institute
US Patent
Affinity DataIC50: >2.00E+4nMAssay Description:BCL-XL/Bad BH3 Peptide (BCL-XL Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-XL solution (usually for a...More data for this Ligand-Target Pair