BDBM186050 US9163011, 4

SMILES COCC[C@@]1(N=C(N)OCC1(F)F)c1nc(NC(=O)c2ncc(cc2C)C#N)ccc1F

InChI Key InChIKey=PSPGXNMAHYIESQ-LJQANCHMSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 186050   

TargetBeta-secretase 1/2(Homo sapiens (Human))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM186050(US9163011, 4)
Affinity DataIC50:  49nMAssay Description:Inhibition of BACE1/BACE2 (unknown origin) transfected in CHO cells assessed as release of amyloid beta (1 to 40) after 24 hrs by immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed