BDBM50579810 CHEMBL5074678

SMILES C[C@]1(CC[C@](CF)(N=C1N)c1cc(NC(=O)c2cc3OCCOc3cn2)ccc1F)S(C)(=O)=O

InChI Key InChIKey=MBCUELYFGMRTJD-FGZHOGPDSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50579810   

TargetBeta-secretase 2(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50579810(CHEMBL5074678)
Affinity DataIC50:  407nMAssay Description:Inhibition of BACE2 (unknown origin) using APP harboring Swedish Lys-Met/Asn-Leu mutant-derived peptide as substrate incubated for 2 hrs by FRET assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50579810(CHEMBL5074678)
Affinity DataIC50:  340nMAssay Description:Inhibition of BACE2 (unknown origin) using APP harboring Swedish Lys-Met/Asn-Leu mutant-derived peptide as substrate incubated for 2 hrs by FRET assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed