BDBM50527023 CHEMBL4449035
SMILES Cn1nc(C(=O)N(CCNc2cc(ccc2F)C(O)=O)Cc2cccc(F)c2)c2COc3ccc(F)cc3-c12
InChI Key InChIKey=YMOMNUUERLHSSV-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50527023
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 46nMAssay Description:Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase re...More data for this Ligand-Target Pair
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Genomics Institute of The Novartis Research Foundation (Gnf)
Curated by ChEMBL
Affinity DataEC50: 24nMAssay Description:Agonist activity at GST-tagged human FXR-LBD (193 to 472 residues) using biotinylated SRC-1 peptide as substrate incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair