BDBM50110590 2,2-Dimethyl-5-(2,5-dimethylphenoxy)valeriansaeure::2,2-Dimethyl-5-(2,5-xylyloxy)valeriansaeure::2,2-Dimethyl-5-(2,5-xylyloxy)valeric acid::5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid::CHEMBL457::GEMFIBROZIL

SMILES Cc1ccc(C)c(OCCCC(C)(C)C(O)=O)c1

InChI Key InChIKey=HEMJJKBWTPKOJG-UHFFFAOYSA-N

Data  4 KI  15 IC50  1 Kd  9 EC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50110590   

TargetBile salt export pump(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50110590(2,2-Dimethyl-5-(2,5-dimethylphenoxy)valeriansaeure...)
Affinity DataIC50: >1.35E+5nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50110590(2,2-Dimethyl-5-(2,5-dimethylphenoxy)valeriansaeure...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed