BDBM451774 US10710980, Example 6::US10947218, Example 6

SMILES Nc1ncc(cc1C(=O)N[C@H]1CC[C@H](O)CC1)-c1ccc(cc1)[C@@]12C[C@@H]1CN(C2)C(CF)CF

InChI Key InChIKey=ZNGBDCDUILRYET-QGKKGPLKSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 451774   

TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451774(US10710980, Example 6 | US10947218, Example 6)
Affinity DataIC50:  5.20E+3nMAssay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for wild-type ALK2 (aa172-499), ALK2 FOP mutant (aa172-499 R20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451774(US10710980, Example 6 | US10947218, Example 6)
Affinity DataIC50:  5.20E+3nMAssay Description:In the applied method, this separation takes place inside a chip that contains a complex capillary system for simultaneous analysis of 12 samples (“1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent