BDBM50337127 2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)-5,11-dimethyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one::CHEMBL1673039::US9266890, IV-1

SMILES COc1cc(ccc1Nc1ncc2N(C)C(=O)c3ccccc3N(C)c2n1)N1CCN(C)CC1

InChI Key InChIKey=DDTPGANIPBKTNU-UHFFFAOYSA-N

Data  6 IC50  6 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337127   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50337127(2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino...)
Affinity DataIC50:  888nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) by AlphaScreen displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed