BDBM50527569 CHEMBL4440098::US11427593, Compound ZB-BD-216

SMILES CCS(=O)(=O)Cc1cnc(Oc2ccc(F)cc2F)c(c1)-c1cc(C)c2n1cc[nH]c2=O

InChI Key InChIKey=UETQFSCWDMJWMM-UHFFFAOYSA-N

Data  11 IC50  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50527569   

TargetBromodomain-containing protein 4 [49-170](Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50527569(CHEMBL4440098 | US11427593, Compound ZB-BD-216)
Affinity DataIC50:  14.1nMAssay Description:AlphaScreen kit (Perkin Elmer) was used to detect effect of the compounds on binding of BRD4 bromodomain to acetylated histone H4 polypeptide. The br...More data for this Ligand-Target Pair
In DepthDetails US Patent