BDBM220664 US10633379, Compound Y::US9296741, 253

SMILES CCNC(=O)c1cc2c(cn(C)c(=O)c2[nH]1)-c1cc(ccc1Oc1ccc(F)cc1F)S(C)(=O)=O

InChI Key InChIKey=GLPRVXBSUHOVMP-UHFFFAOYSA-N

Data  8 KI

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 220664   

TargetBromodomain-containing protein 4 [57-168](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM220664(US10633379, Compound Y | US9296741, 253)
Affinity DataKi:  20.4nM ΔG°:  -10.5kcal/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBromodomain-containing protein 4 [57-168](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM220664(US10633379, Compound Y | US9296741, 253)
Affinity DataKi:  69.9nMAssay Description:Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB