BDBM374747 US10246467, Example I-29::US10919913, # I-29
SMILES C[C@H]1Oc2n(nc3cc(ccc23)C(O)=O)[C@H]2[C@@H]1N(CC1CC1)[C@@]1([C@@H]2c2cccc(Cl)c2F)C(=O)Nc2cc(Cl)ccc12
InChI Key InChIKey=SDVAEDVASKNSQX-IREGEPEUSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 374747
TargetCellular tumor antigen p53 [16-27]/E3 ubiquitin-protein ligase Mdm2 [23-117](Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 520nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair