BDBM50001584 CHEMBL3237442::US8841312, 1

SMILES C1CCC(C1)n1c2cnccc2c2cnc(Nc3ccc(cn3)N3CCNCC3)nc12

InChI Key InChIKey=MCPPMOSBWNMSOA-UHFFFAOYSA-N

Data  6 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50001584   

TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM50001584(CHEMBL3237442 | US8841312, 1)
Affinity DataIC50:  4.40nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair