BDBM214688 US9295672, (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol

SMILES Cc1cc(Nc2nc(nc3ccccc23)C(O)c2ccc(F)cc2)n[nH]1

InChI Key

Data  7 IC50  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 214688   

TargetCytochrome P450 2C8(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM214688(US9295672, (4-fluorophenyl)(4-((5-methyl-1H-pyraz...)
Affinity DataIC50:  2.31E+4nMT: 2°CAssay Description:The ability of the R and S enantiomers of (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol to inhibit the common drug met...More data for this Ligand-Target Pair
In DepthDetails US Patent