BDBM261496 US10011568, Ex. No. 20::US9708266, 20

SMILES CN(C(=O)C(C)(C)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1c(nc(cc1-c1ccc(F)cc1C)[C@H]1CC[C@H](CC(O)=O)CC1)C#N

InChI Key InChIKey=GHXADUNCOKFSDJ-MXVIHJGJSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 261496   

TargetCytochrome P450 3A4(Human)
Kissei Pharmaceutical

US Patent
LigandPNGBDBM261496(US10011568, Ex. No. 20 | US9708266, 20)
Affinity DataIC50:  5.50E+3nMAssay Description:A dimethyl sulfoxide (DMSO) solution of a test compound with a concentration 1000 times higher than the evaluation concentration was prepared, and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetCytochrome P450 3A4(Human)
Kissei Pharmaceutical

US Patent
LigandPNGBDBM261496(US10011568, Ex. No. 20 | US9708266, 20)
Affinity DataIC50:  5.50E+3nMpH: 7.4 T: 25°CAssay Description:A dimethyl sulfoxide (DMSO) solution of a test compound with a concentration 1000 times higher than the evaluation concentration was prepared, and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent