BDBM50184807 (R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[1,2-f][1,2,4]triazin-6-yloxy)propan-2-ol::(R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy)propan-2-ol::BMS-540215::CHEMBL377300

SMILES C[C@@H](O)COc1cn2ncnc(Oc3ccc4[nH]c(C)cc4c3F)c2c1C

InChI Key InChIKey=WCWUXEGQKLTGDX-LLVKDONJSA-N

Data  4 KI  21 IC50  442 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50184807   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibitory activity against CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of human CYP3A4 using 7-benzyloxyresorufinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human CYP3A4 using 7-benzyl-trifluoromethyl coumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed