BDBM50548385 Glpg-1205::Glpg1205

SMILES O=c1nc(OC[C@@H]2COCCO2)cc2-c3ccc(cc3CCn12)C#CC1CC1

InChI Key InChIKey=IRBAWVGZNJIROV-SFHVURJKSA-N

Data  1 KI  11 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50548385   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50548385(Glpg-1205 | Glpg1205)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human CYP3A4 in human liver microsomes using testosterone as substrate and in presence of co-factor preincubated for 20 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50548385(Glpg-1205 | Glpg1205)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate and in presence of co-factor preincubated for 20 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50548385(Glpg-1205 | Glpg1205)
Affinity DataIC50: >5.00E+4nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using testosterone as substrate and in presence of co-factor by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50548385(Glpg-1205 | Glpg1205)
Affinity DataIC50: >5.00E+4nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate and in presence of co-factor by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed