BDBM50240510 CHEMBL898::DIFLUNISAL

SMILES OC(=O)c1cc(ccc1O)-c1ccc(F)cc1F

InChI Key InChIKey=HUPFGZXOMWLGNK-UHFFFAOYSA-N

Data  8 KI  10 IC50  9 Kd  4 EC50

PDB links: 9 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50240510   

TargetDihydrofolate reductase(Homo sapiens (Human))
University of Tennessee

Curated by ChEMBL
LigandPNGBDBM50240510(CHEMBL898 | DIFLUNISAL)
Affinity DataKi:  3.40E+4nMAssay Description:Inhibition of human DHFR in presence of DHF and NADPH by UV-vis spectrometry by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed