BDBM651960 N-(1-(1H-1,2,4-triazol-3-yl) ethyl)-4-(3-fluoro-4-(trifluoromethyl)benzyl)-3-methyl-1H-pyrrole-2-carboxamide::US11903936, Compound 5
SMILES CC(NC(=O)c1[nH]cc(Cc2ccc(c(F)c2)C(F)(F)F)c1C)c1nc[nH]n1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 651960
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
The Board Of Regents Of The University Of Texas System
US Patent
The Board Of Regents Of The University Of Texas System
US Patent
Affinity DataIC50: 110nMAssay Description:The 50% inhibitory concentration (IC50) for the described compounds was determined using the 2,6-dichloroindophenol (DCIP) assay to monitor the DHODH...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
The Board Of Regents Of The University Of Texas System
US Patent
The Board Of Regents Of The University Of Texas System
US Patent
Affinity DataEC50: 39nMAssay Description:P. falciparum 3D7 cells were grown in RPMI media supplemented with 0.5% albuMAX I, human red blood cells to 0.5% hematocrit and 0.5% parasitemia as d...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
The Board Of Regents Of The University Of Texas System
US Patent
The Board Of Regents Of The University Of Texas System
US Patent
Affinity DataIC50: >1.00E+5nMAssay Description:The 50% inhibitory concentration (IC50) for the described compounds was determined using the 2,6-dichloroindophenol (DCIP) assay to monitor the DHODH...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. vivax)
The Board Of Regents Of The University Of Texas System
US Patent
The Board Of Regents Of The University Of Texas System
US Patent
Affinity DataIC50: 61nMAssay Description:The 50% inhibitory concentration (IC50) for the described compounds was determined using the 2,6-dichloroindophenol (DCIP) assay to monitor the DHODH...More data for this Ligand-Target Pair