BDBM400651 US10000476, Compound I-10::US10000476, Compound I-153

SMILES Cc1cccn(CC2(NC(=O)NC2=O)c2ccc(F)c(F)c2)c1=O

InChI Key InChIKey=HEHGUDVOXPGLAU-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 400651   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Kaken Pharmaceutical

US Patent
LigandPNGBDBM400651(US10000476, Compound I-10 | US10000476, Compound I...)
Affinity DataIC50: <100nMAssay Description:The TACE inhibition test was carried out by measuring TACE activity in the presence and the absence of the test substance using the thus-obtained TAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Kaken Pharmaceutical

US Patent
LigandPNGBDBM400651(US10000476, Compound I-10 | US10000476, Compound I...)
Affinity DataIC50: <100nMAssay Description:The TACE inhibition test was carried out by measuring TACE activity in the presence and the absence of the test substance using the thus-obtained TAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent