BDBM50236619 CHEMBL4070236
SMILES [H][C@]12CC[C@]([H])(O1)[C@@H]([C@@H]2N(C)S(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO
InChI Key InChIKey=WQWVTFKKGIYLJY-UARRHKHWSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50236619
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant TACE catalytic domain (unknown origin) using Abz-LAQAVRSSSR-Dpa as substrate preincubated for 10 mins followed by substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of fibrinogen binding to integrin alphaIIb-beta3More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of TACE in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated TNFalpha production pretreated for 1 hr followed by LPS stimulati...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]-5-HT binding to serotonin transporter of rat brain synaptosomesMore data for this Ligand-Target Pair