BDBM202384 US10081606, Compound I-16::US9238629, I-16::US9765038, Compound I-16

SMILES COc1cccc(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)c1OC

InChI Key InChIKey=NBLFLERZTPRKQT-UHFFFAOYSA-N

Data  6 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202384   

TargetEpidermal growth factor receptor [1-745,751-967](Homo sapiens (Human))
Celgene Avilomics Research

US Patent
LigandPNGBDBM202384(US10081606, Compound I-16 | US9238629, I-16 | US97...)
Affinity DataEC50: <10nMAssay Description:To assess phosphor-EGFR signaling, blots were probed with rabbit anti-Phospho-EGFR (Y1068) and mouse total anti-EGFR antibodies. Phospho-EGFR signal ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent