BDBM50146440 8-Ethylsulfanyl-3-methyl-5-pyrazin-2-yl-3,4-dihydro-2H-naphthalen-1-one::CHEMBL318370

SMILES CCSc1ccc(-c2cnccn2)c2CC(C)CC(=O)c12

InChI Key InChIKey=LGRQUGHDTPHNOB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50146440   

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50146440(8-Ethylsulfanyl-3-methyl-5-pyrazin-2-yl-3,4-dihydr...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of [3H]-Ro- 15-1788 binding to human GABA-A receptor alpha-5-beta-3-gamma-2 subunitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed