BDBM381346 4-chloro-N-(4-isopropylphenyl)-3- methyl-1-(1-methylpiperidin-4-yl)- 1H-pyrazolo[3,4-b]pyridine-5- carboxamide::US10272074, Example 179
SMILES CC(C)c1ccc(NC(=O)c2cnc3n(nc(C)c3c2Cl)C2CCN(C)CC2)cc1
InChI Key InChIKey=GAKVHOVEBOFSGM-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 381346
TargetGlucocorticoid receptor(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataIC50: <50nMAssay Description:The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...More data for this Ligand-Target Pair