BDBM50280810 5-{2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-1-hydroxy-ethyl}-1,3-dihydro-indol-2-one::CHEMBL173092

SMILES OC(CN1CCC(Cc2ccc(F)cc2)CC1)c1ccc2NC(=O)Cc2c1

InChI Key InChIKey=JZAYUGIZPPLLGT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50280810   

TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50280810(5-{2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-1-hydrox...)
Affinity DataIC50:  600nMAssay Description:Tested for the NMDA antagonist activity using a functional assay, by protection of cultured hippocampus neurons from the toxic effects of extracellul...More data for this Ligand-Target Pair
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