BDBM50316226 (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide::CHEMBL1094636::MK-4827::Niraparib

SMILES NC(=O)c1cccc2cn(nc12)-c1ccc(cc1)[C@@H]1CCCNC1

InChI Key InChIKey=PCHKPVIQAHNQLW-CQSZACIVSA-N

Data  2 KI  55 IC50  9 Kd  2 EC50

PDB links: 5 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50316226   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50316226((S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-car...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human GSK-3beta expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric s...More data for this Ligand-Target Pair
In DepthDetails PubMed