BDBM36527 1,6-dimethyl-3-phenyl-1H,5H,6H,7H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione, 10::US9073941, 601
SMILES Cn1nc(nc2c1nc(=O)n(C)c2=O)-c1ccccc1
InChI Key InChIKey=SFOMBJIIZPCRJH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 36527
Affinity DataKd: 585nMAssay Description:AlphaScreen technology based high-throughput (ALPHA) assay is used to identify inhibitors of Hsp90-TPR2A interaction.More data for this Ligand-Target Pair
Affinity DataEC50: 690nMT: 2°CAssay Description:Cell assay using BT474, SKBR3 and MCF-12F cell lines measured by WST-1 colorimetric cell proliferation assay.More data for this Ligand-Target Pair
Affinity DataKd: 1.00E+3nMpH: 8.0Assay Description:A fluorescence polarization (FP) assay monitor the fluorescein-labeled C-terminal Hsp90 peptide-TPRA interaction. FP assay will also confirm binding...More data for this Ligand-Target Pair