BDBM50585813 CHEMBL5072532

SMILES CCOP(=O)(Cn1ccc(NC(=O)c2cc(OC(C)C)cc(Oc3cnc(cn3)C(=O)N3CCC3)c2)n1)OCC

InChI Key InChIKey=OYUDYQMFVRHPIY-UHFFFAOYSA-N

Data  10 IC50  4 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50585813   

TargetHexokinase-4(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585813(CHEMBL5072532)
Affinity DataEC50:  53nMAssay Description:Activation of recombinant human full length liver glucokinase expressed in Escherichia coli incubated for 10 mins in presence of 5 mM glucose by plat...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585813(CHEMBL5072532)
Affinity DataEC50:  29nMAssay Description:Activation of recombinant full length human liver glucokinase expressed in Escherichia coli incubated for 10 mins by plate reader analysisMore data for this Ligand-Target Pair
TargetHexokinase-4(Mus musculus (Mouse))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585813(CHEMBL5072532)
Affinity DataEC50:  32nMAssay Description:Activation of recombinant mouse full length liver glucokinase expressed in Escherichia coli incubated for 10 mins in presence of 12 mM glucose by pla...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585813(CHEMBL5072532)
Affinity DataIC50:  123nMAssay Description:Displacement of fluorescent labeled derivative from recombinant human hepatic glucokinase incubated for 30 mins in presence of 12 mM glucose by fluor...More data for this Ligand-Target Pair
TargetHexokinase-4(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585813(CHEMBL5072532)
Affinity DataEC50:  148nMAssay Description:Activation of recombinant human full length liver glucokinase expressed in Escherichia coli incubated for 10 mins in presence of 2 mM glucose by plat...More data for this Ligand-Target Pair