BDBM515358 (13E,14E,22R,24S)-12-amino-24,35-difluoro- 4-oxa-9- aza-1(5,3)-pyrazolo[1,5-a] pyrimidine-3(3,2)-pyridine-2(1,2)- pyrrolidylcyclodecanephane-10-one::US11098060, Example 16

SMILES Nc1nn2ccc3nc2c1C(=O)NCCCCOc1ncc(F)cc1[C@H]1C[C@H](F)CN31

InChI Key InChIKey=SCHVWLCTSXIZAS-GXTWGEPZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 515358   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM515358((13E,14E,22R,24S)-12-amino-24,35-difluoro- 4-oxa-9...)
Affinity DataIC50:  0.510nMAssay Description:A testing platform for TrkAWT kinase activity was established based on Homogeneous Time-Resolved Fluorescence (HTRF) assay, and the activities of the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent