BDBM50312629 CHEMBL1088736::Octanedioic Acid-{3-[1-(3,5-Bis(hydroxymethyl)phenyl)-1H-[1,2,3]-triazol-4-yl]phenyl}amide-Hydroxyamide

SMILES OCc1cc(CO)cc(c1)-n1cc(nn1)-c1cccc(NC(=O)CCCCCCC(=O)NO)c1

InChI Key InChIKey=DAFYMIICLGKZQP-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50312629   

TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50312629(CHEMBL1088736 | Octanedioic Acid-{3-[1-(3,5-Bis(hy...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of HDAC1 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed