BDBM53262 2-[4-[(4-chlorophenyl)sulfonylamino]-1-hydroxynaphthalen-2-yl]sulfanylacetic acid::2-[4-[(4-chlorophenyl)sulfonylamino]-1-oxidanyl-naphthalen-2-yl]sulfanylethanoic acid::2-[[4-[(4-chlorophenyl)sulfonylamino]-1-hydroxy-2-naphthalenyl]thio]acetic acid::2-[[4-[(4-chlorophenyl)sulfonylamino]-1-hydroxy-2-naphthyl]thio]acetic acid::MLS001196186::SMR000558496::[(4-{[(4-chlorophenyl)sulfonyl]amino}-1-hydroxy-2-naphthyl)thio]acetic acid::cid_1309516

SMILES OC(=O)CSc1cc(NS(=O)(=O)c2ccc(Cl)cc2)c2ccccc2c1O

InChI Key InChIKey=NLRVCTAQYTWYQX-UHFFFAOYSA-N

Data  2 KI  4 IC50  1 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 53262   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM53262(2-[4-[(4-chlorophenyl)sulfonylamino]-1-hydroxynaph...)
Affinity DataKi:  820nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
University Of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM53262(2-[4-[(4-chlorophenyl)sulfonylamino]-1-hydroxynaph...)
Affinity DataIC50:  2.70E+3nMAssay Description:Binding affinity to His-tagged MCL1 (171 to 327) (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as inhibition of MCL1-N-terminal b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed