BDBM562345 12-Ethyl-8,9,11-trimethyl-1-(3-(naphthalen-1-yloxy)propyl)-5,6,9,11-tetrahydro-4H,8H-pyrazolo[3′,4′:4,5][1]thia[2,8]diazacycloundecino[6,7,8-hi]indole-2-carboxylic acid 7,7-dioxide (Mixture of Stereoisomers)::US11401278, Example 18

SMILES CCc1c-2c(nn1C)C(C)N(C)S(=O)(=O)CCCn1c(C(O)=O)c(CCCOc3cccc4ccccc34)c3cccc-2c13

InChI Key InChIKey=CYAZPSVAIWRWMS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 562345   

LigandPNGBDBM562345(12-Ethyl-8,9,11-trimethyl-1-(3-(naphthalen-1-yloxy...)
Affinity DataIC50:  7.80nMAssay Description:MCL-1/Noxa BH3 Peptide (MCL-1 Assay): From there, 50 nl were transferred in a dark test plate (Greiner Bio-One, Frickenhausen, Germany). The assay wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent