BDBM319601 US10174007, Example 40::US10787438, Example 40::US11634410, Example 40::[(1R,5S,6R)-3-{5-chloro-6-(difluoromethyl)-2-[(2S)-2-methylazetidin-1-yl]pyrimidin-4-yl}-3-azabicyclo[3.1.0]hex-6-yl]acetic acid

SMILES C[C@H]1CCN1c1nc(C(F)F)c(Cl)c(n1)N1C[C@H]2[C@H](CC(O)=O)[C@H]2C1

InChI Key InChIKey=AFUXAZPXNHXKOK-AATLWQCWSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 319601   

TargetIsoform A of Ketohexokinase (Peripheral)(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM319601(US10174007, Example 40 | US10787438, Example 40 | ...)
Affinity DataIC50:  37.9nMAssay Description:Assay D, was performed using human KHK-A to assess the potency of compounds in inhibiting activity of this enzyme. Compounds were prepared in DMSO as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent