BDBM220371 US9290488, E53a(i)
SMILES CC1(C)[C@@H]2C[C@H]1[C@H](CCN1[C@H]3CCC[C@@H]1C[C@@H](C3)n1c3ccccc3nc(N3CC[C@@H]3C(O)=O)c1=O)CC2
InChI Key InChIKey=OPNHKXQPNQNQOK-DUWFNVGLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 220371
Affinity DataKi: 128nM ΔG°: -9.40kcal/molepH: 7.4 T: 25°CAssay Description:Radioligand dose displacement assays used 0.4-0.8 nM [3H]-U69,593 (NEN; 40 Ci/mmole) with 10-20 μg membrane protein (recombinant kappa opioid rece...More data for this Ligand-Target Pair
Affinity DataEC50: >2.00E+4nMpH: 7.4 T: 25°CAssay Description:Kappa opioid receptor membrane solution was prepared by sequentially adding final concentrations of 0.026 μg/μL kappa membrane protein (in-hous...More data for this Ligand-Target Pair