BDBM273188 (R)-1-(7-ethyl-6-fluoro-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl)-N-[(5-methylpyrazin-2-yl)methyl]pyrrolidine-2-carboxamide::US10065972, Example 685
SMILES CCc1nc2sc(nn2c(=O)c1F)N1CCC[C@@H]1C(=O)NCc1cnc(C)cn1
InChI Key InChIKey=BPKIJBCPTYHZME-CYBMUJFWSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 273188
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
US Patent
Mitsubishi Tanabe Pharma
US Patent
Affinity DataIC50: 2.20E+3nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair