BDBM270495 3-[({(1R)-6-[methyl(4-methyl-phenyl)amino]-1,2,3,4-tetrahydroisoquinolyl} methyl)amino] pyridine-4-carboxylic acid::US10059687, Example 1B::US11001568, Example 1B::US11731954, Example 1B

SMILES CN(c1ccc(C)cc1)c1ccc2[C@H](CNc3cnccc3C(O)=O)NCCc2c1

InChI Key InChIKey=BWZXDTADOZVXSQ-QHCPKHFHSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 270495   

TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM270495(3-[({(1R)-6-[methyl(4-methyl-phenyl)amino]-1,2,3,4...)
Affinity DataIC50:  550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM270495(3-[({(1R)-6-[methyl(4-methyl-phenyl)amino]-1,2,3,4...)
Affinity DataIC50:  550nMAssay Description:JMJD2C: The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM270495(3-[({(1R)-6-[methyl(4-methyl-phenyl)amino]-1,2,3,4...)
Affinity DataIC50:  550nMAssay Description:JMJD2C: The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM270495(3-[({(1R)-6-[methyl(4-methyl-phenyl)amino]-1,2,3,4...)
Affinity DataIC50:  550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent