BDBM50603918 CHEMBL5206450::US11873292, Compound A21

SMILES CC1(CNC2CC2c2ccc3N(CCc3c2)S(=O)(=O)c2ccccc2)CCNCC1

InChI Key InChIKey=OZGYPGKEBOFBFZ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50603918   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50603918(CHEMBL5206450 | US11873292, Compound A21)
Affinity DataIC50:  17.1nMAssay Description:Principle: LSD1 specifically removes the methylation modification at K4 lysine on H3 polypeptide substrate, making it a substrate without methylation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50603918(CHEMBL5206450 | US11873292, Compound A21)
Affinity DataIC50:  1.71E+4nMAssay Description:Inhibition of N-terminal His/GST-tagged human LSD1 (172 to 852 residues) expressed in expressed in baculovirus infected insect cells using biotinylat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed