BDBM50603918 CHEMBL5206450::US11873292, Compound A21
SMILES CC1(CNC2CC2c2ccc3N(CCc3c2)S(=O)(=O)c2ccccc2)CCNCC1
InChI Key InChIKey=OZGYPGKEBOFBFZ-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50603918
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Shanghai Institute of Materia Medica
US Patent
Shanghai Institute of Materia Medica
US Patent
Affinity DataIC50: 17.1nMAssay Description:Principle: LSD1 specifically removes the methylation modification at K4 lysine on H3 polypeptide substrate, making it a substrate without methylation...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Shanghai Institute of Materia Medica
US Patent
Shanghai Institute of Materia Medica
US Patent
Affinity DataIC50: 1.71E+4nMAssay Description:Inhibition of N-terminal His/GST-tagged human LSD1 (172 to 852 residues) expressed in expressed in baculovirus infected insect cells using biotinylat...More data for this Ligand-Target Pair