BDBM454276 (Z)-3-fluoro-4-(5-methoxy-2-methyl-3-(3- (methylsulfonyl)phenyl)-1H-pyrrolo[3,2- b]pyridin-1-yl)but-2-en-1-amine::US10717733, Compound 69::US11098045, Compound 69

SMILES COc1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(C)(=O)=O)c2n1

InChI Key InChIKey=LONHJBOQCASDGC-DHDCSXOGSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 454276   

TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

US Patent
LigandPNGBDBM454276((Z)-3-fluoro-4-(5-methoxy-2-methyl-3-(3- (methylsu...)
Affinity DataIC50: <300nMAssay Description:LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

US Patent
LigandPNGBDBM454276((Z)-3-fluoro-4-(5-methoxy-2-methyl-3-(3- (methylsu...)
Affinity DataIC50: <300nMAssay Description:LOX: The assay was developed using either 384 or 96 well format. Briefly, in a standard 384 well plate assay 25 μL of a dilution of any of the i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent