BDBM447649 6-((3-methoxy-4-((2-methylpyrimidin-5-yl)methoxy)phenyl)amino)-3-morpholinoquinoxaline-5-carbonitrile::US10689362, Example 128

SMILES COc1cc(Nc2ccc3ncc(nc3c2C#N)N2CCOCC2)ccc1OCc1cnc(C)nc1

InChI Key InChIKey=VGTIMEXCZRHVQQ-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 447649   

TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Development Center For Biotechnology

US Patent
LigandPNGBDBM447649(6-((3-methoxy-4-((2-methylpyrimidin-5-yl)methoxy)p...)
Affinity DataIC50:  275nMAssay Description:CSF-1R: Inhibition of CSF-1R kinase activity by a test compound disclosed herein was estimated by AlphaScreen (PerkinElmer). Standard assay condition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent