BDBM17015 (3Z)-3-(1H-pyrrol-2-ylmethylidene)-2,3-dihydro-1H-indol-2-one::CHEMBL86755::Indolinone based inhibitor, 1::Oxindole I

SMILES O=C1Nc2ccccc2\C1=C\c1ccc[nH]1

InChI Key InChIKey=SEZFNTZQMWJIAI-FLIBITNWSA-N

Data  15 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17015   

TargetMacrophage colony-stimulating factor 1 receptor [538-972]()
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17015((3Z)-3-(1H-pyrrol-2-ylmethylidene)-2,3-dihydro-1H-...)
Affinity DataIC50:  1.20E+3nMpH: 7.5 T: 2°CAssay Description:The full-length cFMS cytoplasmic domain (FMS.538-972.6His) or chimera was incubated with compound in reaction buffer. Control reactions were run in e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed