BDBM194644 US9206139, 3

SMILES FC(F)(F)c1ccc(C[C@@H](C2CC2)C(=O)NC[C@]2(NC(=O)NC2=O)C2CC2)cc1

InChI Key InChIKey=JHOUEQAOHDTLPY-KXBFYZLASA-N

Data  24 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 194644   

TargetMatrix metalloproteinase-14(Human)
Eli Lilly

US Patent
LigandPNGBDBM194644(US9206139, 3)
Affinity DataIC50:  5.02E+4nMpH: 7.5Assay Description:A continuous assay is used in which the substrate is a synthetic peptide containing a fluorescent group (7-methoxycoumarin, Mca), which is quenched b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetMatrix metalloproteinase-14(Human)
Eli Lilly

US Patent
LigandPNGBDBM194644(US9206139, 3)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human MMP14 using Mca-PQGL-(3-[2, 4-dinitrophenyl]-L-2, 3-diaminopropionyl)-AR-OH as substrate after 2 to 4 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed