BDBM50283472 CHEMBL4160748

SMILES COc1ccc(-c2c(C)nn3c(cc(C)nc23)C(F)(F)F)c(F)c1F

InChI Key InChIKey=NYBZCKAQIIPSDS-UHFFFAOYSA-N

Data  1 KI  10 IC50  14 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283472   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283472(CHEMBL4160748)
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu5 receptor expressed in HEK cells assessed as decrease in glutamate-induced thallium flux incubated for 142...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50283472(CHEMBL4160748)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of rat mGlu5 receptor expressed in HEK cells assessed as increase in glutamate-induced calcium flux incubated for 142 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed