BDBM50492391 CHEMBL2401999
SMILES Cc1ccc(cc1NC(=O)c1ccc(s1)-c1cncc(F)c1)C(=O)NC1CC1
InChI Key InChIKey=GWAMNECAZIXYSS-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50492391
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of p38 MAPK-mediated TNFalpha production in LPS-induced human whole blood preincubated for 5 mins prior to LPS-treatment measured after 6 ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of p38 MAPK-mediated TNFalpha production in LPS-induced human PBMC preincubated for 5 mins prior to LPS-treatment measured after 6 hrs by ...More data for this Ligand-Target Pair