BDBM50492391 CHEMBL2401999

SMILES Cc1ccc(cc1NC(=O)c1ccc(s1)-c1cncc(F)c1)C(=O)NC1CC1

InChI Key InChIKey=GWAMNECAZIXYSS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50492391   

TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50492391(CHEMBL2401999)
Affinity DataIC50:  6nMAssay Description:Inhibition of p38 MAPK-mediated TNFalpha production in LPS-induced human whole blood preincubated for 5 mins prior to LPS-treatment measured after 6 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50492391(CHEMBL2401999)
Affinity DataIC50:  150nMAssay Description:Inhibition of p38 MAPK-mediated TNFalpha production in LPS-induced human PBMC preincubated for 5 mins prior to LPS-treatment measured after 6 hrs by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed