BDBM13531 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole::4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol::4-[4-(4-fluorophenyl)-5-(4-pyridyl)-4-imidazolin-2-ylidene]cyclohexa-2,5-dien-1-one::4-[5-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-imidazol-2-yl]phenol::SB-202190::SB202190::biotinylated SB202190
SMILES Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1
InChI Key InChIKey=QHKYPYXTTXKZST-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 13531
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
Affinity DataKd: 13nMAssay Description:Average Binding Constant for p38-alpha; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of p38alpha by Cherenkov countingMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of His-tagged human SAPK2a/p38 expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of p38alphaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for TGFBR1 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 9.80nMAssay Description:Binding constant for full-length p38-alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant p38alpha assessed as [gamma33P]ATP utilization by microplate scintillation countingMore data for this Ligand-Target Pair