BDBM50175745 7-(1-tert-butylpiperidin-4-yl)-1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)quinolin-2(1H)-one::CHEMBL199679
SMILES CC(C)(C)N1CCC(CC1)c1cc(-c2ccc(F)cc2F)c2ccc(=O)n(-c3c(Cl)cccc3Cl)c2c1
InChI Key InChIKey=YQMXHHPOKLHLOD-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50175745
Affinity DataIC50: 1.70nMAssay Description:Inhibition of TNF alpha release in THP1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:Inhibition of P38 alpha MAPKMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of wild type p38alpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of LPS stimulated TNF alpha release in whole bloodMore data for this Ligand-Target Pair