BDBM50451549 CHEMBL4207737

SMILES COc1ccc(CNC(=O)c2sc3nnc(C)c(C)c3c2N)cc1F

InChI Key InChIKey=VFNHDIWHQGVWLL-UHFFFAOYSA-N

Data  5 IC50  10 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50451549   

TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))TBA
LigandPNGBDBM50451549(CHEMBL4207737)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulator activity at human M2 receptor expressed in CHO cells co-expressing Gqi5 assessed as maximal response to ACh by calcium ...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50451549(CHEMBL4207737)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulator activity at rat M2 receptor expressed in CHO cells co-expressing Gqi5 assessed as maximal response to ACh by calcium mo...More data for this Ligand-Target Pair
In DepthDetails PubMed