BDBM29589 Faridak::LBH-589::LBH-589B::Panobinostat::US10722597, Compound Panobinostat
SMILES Cc1[nH]c2ccccc2c1CCNCc1ccc(\C=C\C(=O)NO)cc1
InChI Key InChIKey=FPOHNWQLNRZRFC-ZHACJKMWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 29589
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Nestle Skin Health R&D
Curated by ChEMBL
Nestle Skin Health R&D
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human recombinant SIRT3 using fluoro-lysine sirtuin 2 deacetylase substrate after 45 mins by fluorimetrc methodMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Nestle Skin Health R&D
Curated by ChEMBL
Nestle Skin Health R&D
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT3 expressed in Escherichia coli using Ac-Arg-His-Lys-Lys(Ac)-AMC as susbtrate after 2 hrs b...More data for this Ligand-Target Pair