BDBM50209245 CHEMBL247378

SMILES [O-][N+](=O)c1cccc2cn[nH]c12

InChI Key InChIKey=PQCAUHUKTBHUSA-UHFFFAOYSA-N

Data  21 IC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50209245   

TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Université

Curated by ChEMBL
LigandPNGBDBM50209245(CHEMBL247378)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of mouse recombinant iNOSMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Université

Curated by ChEMBL
LigandPNGBDBM50209245(CHEMBL247378)
Affinity DataIC50:  2.00E+4nMAssay Description:Tested to inhibit the conversion of [3H]-L-arginine to [3H]-L-citrulline catalyzed by inducible NOS from mouse macrophage J774 cellsMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50209245(CHEMBL247378)
Affinity DataIC50:  2.40E+4nMAssay Description:Tested to inhibit the conversion of [3H]-L-arginine to [3H]-L-citrulline catalyzed by inducible NOS from human DLD-1 cells.More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50209245(CHEMBL247378)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of NOS2More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Université

Curated by ChEMBL
LigandPNGBDBM50209245(CHEMBL247378)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli assessed as conversion of [gamma-14C]L-arginine to [14C]L-citrulline by radioactiv...More data for this Ligand-Target Pair