BDBM50550657 CHEMBL4792737

SMILES COc1ccc2Sc3c(Cc2c1)cccc3-c1cc(=O)cc(o1)N1CCOCC1

InChI Key InChIKey=CIZOSCVUGRBXEZ-UHFFFAOYSA-N

Data  4 KI  7 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50550657   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50550657(CHEMBL4792737)
Affinity DataKi:  15nMAssay Description:Inhibition of full length recombinant GST-tagged human VPS34 expressed in baculovirus expression system using PI/PS as substrate incubated for 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50550657(CHEMBL4792737)
Affinity DataKi:  15nMAssay Description:Inhibition of rat neutrophil 5- Lipoxygenase (5-LO), (at a concentration of 0.2 nM ),More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50550657(CHEMBL4792737)
Affinity DataIC50:  29nMAssay Description:Inhibition of recombinant full-length human VPS34 incubated for 60 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Charles River

Curated by ChEMBL
LigandPNGBDBM50550657(CHEMBL4792737)
Affinity DataKd:  5.10nMAssay Description:Binding affinity to human Vps34 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed