BDBM50274638 CHEMBL4126156::US10858355, Example 4

SMILES C[C@@H](C1CC1)N1Cc2cc(cc(c2C1=O)S(C)(=O)=O)-c1sc(NC(C)=O)nc1C

InChI Key InChIKey=PAQUFWFUOVDUIO-NSHDSACASA-N

Data  1 KI  18 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274638   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL

LigandBDBM50274638(CHEMBL4126156 | US10858355, Example 4)Copy SMILESCopy InChI

Affinity DataIC50:  7.94E+3nMAssay Description:Inhibition of recombinant human 6His-tagged PI3K p110alpha/p85alpha using DiC8-PIP2 as substrate preincubated for 10 mins followed by substrate addit...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails ArticlePubMed
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