BDBM50342298 CHEMBL4159325::US11534443, Example 25

SMILES COCCOc1cc(cc2c(C)nc(N)nc12)-c1cnc(OC)c(NS(=O)(=O)c2ccc(F)cc2F)c1

InChI Key InChIKey=YHSZNUBPVWCMDZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50342298   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50342298(CHEMBL4159325 | US11534443, Example 25)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate by Kinase-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed