BDBM50240975 CHEMBL4084907

SMILES Nc1cc(c(cn1)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1)C(F)(F)F

InChI Key InChIKey=ADGGYDAFIHSYFI-UHFFFAOYSA-N

Data  8 KI  16 IC50  9 Kd

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50240975   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
University of Basel

Curated by ChEMBL
LigandPNGBDBM50240975(CHEMBL4084907)
Affinity DataIC50:  451nMAssay Description:Displacement of [3H]baclofen from gamma-aminobutyric-acid B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
University of Basel

Curated by ChEMBL
LigandPNGBDBM50240975(CHEMBL4084907)
Affinity DataIC50:  708nMAssay Description:Inhibition of PI3Kdelta (unknown origin) expressed in baculovirus expression system using L-alpha-phosphatidylinositol as substrate by luminescence a...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
University of Basel

Curated by ChEMBL
LigandPNGBDBM50240975(CHEMBL4084907)
Affinity DataKd:  25nMAssay Description:Binding affinity to human PI3Kdelta (R108 to Q1044 residues) expressed in mammalian expression system by Kinomescan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed